Illustration created for Shadowrun 20th anniversary edition. © 20052009 WizKids Inc.
Second Illustration for Shadowrun SR4A.
The illustration shows a sudden 'Goblinisation' when magic returns to the world. This particular chap is suddenly changing into an ork - lucky him.
Photoshop. From memory a few downloaded brushes were used ... can't quite remember exactly which ones, but check out Leventep's [link]
... amazing stuff!